A study conducted by the NYU Langone Medical Center and sponsored by a leg of the National Cancer Institute has turned up promising results regarding a new technique that may be used to accurately detect mesothelioma at its earliest stages.
Utilizing a technique originally created by Somalogic that uses SOMAmers (or chemically modified single-stranded DNA molecules that bind only to targeted proteins) researchers at the Langone Center conducted a blind test involving 90 blood samples from patients diagnosed with malignant mesothelioma and 80 from participants who were previously exposed to asbestos.
The test was designed to judge the ability of the SOMAmers to detect the presence and quantity of 19 protein biomarkers that manifest themselves in the earlier stages of malignant pleural mesothelioma cases. In that regard, the results were quite promising as the SOMAmers detected 15 of the 19 stage one or two malignant pleural mesothelioma cases amongst the samples.
The study also found that SOMAmers were approximately 80 percent sensitive in identifying diseases, and 100 percent specific in its diagnosis with no false positives.
“The only patients that seem to benefit from therapy in mesothelioma are those that are found in stage 1, and this is only 10 to 15 percent of patients,” said Dr. Harvey I. Pass, the director of the Division of Thoracic Surgery and Thoracic Oncology at the Langone Medical Center and the NYU Cancer Institute. “Moreover, when found early, the magnitude of the operation necessary to reduce the burden of disease may be less, making the patient better able to cope if the disease recurs and the patient needs more aggressive therapy,” he added.
Results of the study will be presented today at the American Association for Cancer Research 102nd Annual Meeting.
If you or a loved one are undergoing mesothelioma treatment and wish to take action against the entities that may be at fault, there may be mesothelioma lawyers who can help you file a mesothelioma lawsuit. If you would like your asbestos law questions answered, please contact Sokolove Law for a free legal consultation to see if you qualify for a mesothelioma attorney to begin the process of pursuing a settlement.